The John F. Hardesty, MD Department of Ophthalmology and Visual Sciences has a longstanding tradition of excellence in patient care, research, and education and is consistently recognized among the nation's leading ophthalmology programs by U.S. News & World Report. With one of the largest ophthalmology research faculties in the country, the department continues to advance the field through groundbreaking discoveries, innovative therapies, and exceptional training programs. Its national research leadership was further affirmed in the 2025 Blue Ridge Institute for Medical Research rankings, in which WashU Medicine Ophthalmology was ranked No. 3 in the nation in National Institutes of Health (NIH) funding among ophthalmology departments. The department secured $22,793,703 in NIH funding across 28 awards led by 19 principal investigators, reflecting the strength of its collaborative research enterprise and its ongoing commitment to improving vision and eye health through scientific innovation.

Our mission is clear: As world leaders in patient care, teaching, and research, we strive to touch lives and preserve and restore vision through innovation and compassionate service.

We invite students to be part of our collaborative and dynamic environment, where they will gain invaluable experience and contribute to groundbreaking discoveries that shape the future of ophthalmology.

While only a small percentage of physicians in the United States specialize in ophthalmology, a fundamental understanding of the eye is essential for all physicians. The eye can provide critical insights into a patient's overall health, aiding in the diagnosis and management of various medical conditions.

A recent Ophthalmology journal article highlighted the widespread relevance of ophthalmology in multiple specialties, stating that "ophthalmology-related issues arise in the diagnosis and treatment of inpatients and outpatients in internal medicine, pediatrics, trauma surgery, neurology, endocrinology, neurosurgery, otolaryngology, dermatology, oncology, and rheumatology services."1

Despite this, many primary care program directors believe that fewer than half of incoming residents possess adequate ophthalmology skills upon entering their internships. Ophthalmoscopy, in particular, remains a significant gap in medical training. Studies have shown that emergency medicine physicians frequently omit ophthalmoscopic examinations even when indicated; when the test is performed, abnormal findings are often missed. This gap in training is especially concerning given the high rate of eye-related emergency department visits: there were 12 million nationwide between 2006 and 2011.

To provide quality care, physicians must either develop proficiency in assessing ocular health or recognize when a referral to an ophthalmologist is necessary. Regardless of specialty, enhancing ophthalmology knowledge strengthens clinical skills and ensures better patient outcomes across all fields of medicine.

1

Graubart EB, Waxman EL, Forster SH, Giaconi JA, Rosenberg JB, Sankar PS, Goyal A, Mirza RG. Ophthalmology objectives for medical students: revisiting what every graduating medical student should know. Ophthalmology, December 2018; 125(12):1842-1843.

Contact Info

Website:http://ophthalmology.wustl.edu

Ophthalmology and Visual Sciences Research Electives

Fourth-year medical students have a variety of opportunities to engage in advanced clinical or research experiences. Below is a list of faculty members with ongoing research projects that actively involve medical students. Students interested in working with a faculty member not listed are encouraged to reach out directly to inquire about potential research opportunities within their lab.

Residents are also encouraged to participate in laboratory or clinical investigations, as research plays a critical role in developing essential skills such as the following:

  • Understanding the limitations of laboratory methodologies
  • Evaluating scientific literature
  • Strengthening critical thinking
  • Refining career goals through hands-on research experience

Residents have the flexibility to choose their research focus, with a broad range of opportunities available. The department supports both basic science and clinical research, with active investigations in the following areas:

  • Neurobiology
  • Immunology
  • Molecular Biology
  • Pharmacology & Physiology
  • Clinical Studies & Outcomes Research

To recognize outstanding contributions, the Rosenbaum Research Award ($1,000) is presented annually to the resident with the most innovative research project.

For a list of available research projects or more information, please contact ophthostudentresearch@wustl.edu.

Interdisciplinary Training in Vision Science (ITVS) Pathway

Graduate students in the Department of Ophthalmology and Visual Sciences (DOVS) come from at least seven different graduate programs, each with distinct course requirements that may not fully cover vision science. To bridge this gap, we developed the Interdisciplinary Training in Vision Science (ITVS) Pathway, a structured curriculum designed to supplement traditional graduate training.

Supported in part by the renewed DOVS T32 grant, the ITVS Pathway offers four specialized courses that introduce students to core aspects of vision science. These courses attract a diverse group of students, postdoctoral fellows, and faculty, fostering a collaborative learning environment where trainees receive mentorship and constructive feedback. Importantly, ITVS students play a key role in refining the program by providing feedback, ensuring that the curriculum continues to evolve to meet the needs of the vision science research community.


Courses


BIOL 5508: ITVS Advanced Techniques

3 course units

The Advanced Methods in Vision Science course provides ITVS students the opportunity to learn about advanced methods utilized in studies of the visual systems from the experts who perform the studies. These methods emerged from different disciplines (molecular biology, imaging, electrophysiology, machine learning), but provide critical details for understanding how the visual systems focuses and processes light stimuli. The course has two components. 1) A series of 90-minute structured discussions of advanced methods via foundational papers and recent applications of these methods. 2) A choice of two hands-on experiences with these methods in the instructor laboratories. We open the discussion section of the course to all students, postdocs, and faculty members (in this order) but cap the class size at 12 participants to facilitate interactions. Hands-on experiences are restricted to ITVS students. For hands-on experiences, each ITVS student chooses two techniques and spends a day in the laboratory of the respective instructor to gain practical experience with the experiments and analysis pipelines and discuss pitfalls and applications of the methods in detail. Through these components, the Advanced Methods in Vision Science course tries to accomplish three goals: 1) enable students to critically assess the literature through an understanding of strengths and limitations of advanced methods, 2) help students plan experiments involving these methods, and 3) facilitate collaborations with experts in the field that could enhance the science of the ITVS students.


BIOL 5509: ITVS Project Building

1 course unit

The overall goal is to have intense guidance to construct a grant/fellowship application. Students should expect to have a near completed F30/F31 application by the end of this course Students will study previous F30/F31 applications and sit on a mock panel to review real world grants from their peers. They will use this experience to understand the reviewers perspective when writing fellowships and grants in the future. Students will draft all portions of a research proposal with feedback from their peers, the course instructor and faculty mentors.


BIOL 5501: The Biology and Pathology of the Visual System

3 course units

The purpose of the course is to provide a fascinating view of vertebrate eye development, anatomy, physiology and pathology. Topics to be covered include the molecules that control eye formation, ocular stem cells, the physiology of transparency, hereditary ocular diseases, phototransduction, the neurobiology of the retina and central visual pathways, age-related eye diseases, and many others. The course is open to all second year graduates students and above. Ophthalmology residents and postdocs with an interest in vision are strongly encouraged to attend.


BIOL 5623: ITVS Translation in Vision Science

1 course unit

This course introduces students to the translation of basic science and pre-clinical research to the biopharma industry and/or clinics to benefit patients. The class will introduce how patient genetics can guide disease research in animal models and how patient tissue can be used to model disease progression/outcomes. Students will learn how results from these types of studies impact patient lives through the development of drug/treatment candidates and/or clinical trials. Students will be connected to clinicians to witness the profound impact of blinding diseases on patient lives and how scientific advances in disease research can motivate philanthropic funding of subsequent research.


Curriculum courses for Ophthalmology and Visual Sciences are listed below.


Gateway Curriculum

WashU’s Gateway Curriculum is designed to provide medical students with a progressive, hands-on learning experience throughout their four-year education. The curriculum is structured into three phases, integrating early clinical exposure with advanced training opportunities to develop well-rounded, patient-centered physicians.

Early Clinical Immersion

The first 16 months of medical school introduce students to foundational medical knowledge and clinical practice. A key component of this phase is the Procedural Immersions, three-week-long experiences that expose students to various clinical and surgical settings. These immersions help students:

  • Familiarize themselves with different healthcare environments.
  • Develop essential clinical skills.
  • Understand the broader impact of society and healthcare systems on individual patient outcomes.

This immersive, 360-degree approach allows students to view patient care from multiple perspectives—physician, patient, and healthcare system. During the Ophthalmology Procedural Immersion, students gain hands-on experience in the University Eye Clinic, pediatric and adult subspecialty clinics, and operating rooms, as well as participate in inpatient consult rounds. This early exposure helps contextualize classroom learning and lays the foundation for future clinical training.

Ophthalmology in the Brain and Behavior Module

Ophthalmology education is integrated into Phase 1 through Module 7: Brain and Behavior, where students explore:

  • Eye anatomy and physiology.
  • Visual pathways in the brain.
  • Extraocular movement mechanisms.

Interactive case-based sessions reinforce these concepts, encouraging critical thinking and the development of fundamental eye examination skills.

Advanced Clinical Training in Ophthalmology

In the final phase of the curriculum, students have the opportunity to further their ophthalmology training through electives and advanced clinical rotations. These experiences provide the following:

  • Deeper exposure to clinical ophthalmology.
  • Hands-on training in diagnosing and managing ocular conditions.
  • Close collaboration with ophthalmology residents.

During these rotations, students refine their diagnostic skills by reviewing differential diagnoses for red eye, interpreting ophthalmologic consult notes, and managing ocular emergencies. Additionally, they gain proficiency in essential examination techniques, including ophthalmoscopy, slit-lamp biomicroscopy, and indirect ophthalmoscopy.

By integrating ophthalmology education throughout the medical school journey, the Gateway Curriculum ensures that students develop the knowledge, skills, and clinical confidence needed to excel in eye care and beyond.

Curriculum Courses


OPHTH 8010 Ophthalmology (Clinical Elective)

The Ophthalmology elective is designed to provide a foundational experience in clinical and surgical ophthalmology for medical students, whether they are interested in ophthalmology or other fields of medicine for their future career. Time will be divided among the University Eye Service clinic, adult inpatient consults, and ophthalmology subspecialties (e.g. Pediatric Ophthalmology, Glaucoma, Cornea, Oculoplastics, and Retina).
   
The amount of time at each location will depend on length of the rotation and the student's specific interests. There are weekly case conferences with Dr. Andrew Lee, Dr. Cynthia Montana, and other faculty members. Students will attend departmental grand rounds weekly, when applicable. At the end of the experience, the student is expected to be familiar with the routine eye exam, common eye conditions and their treatment, and the use of the slit lamp and ophthalmoscope.

Credit 2 units.

Typical periods offered: Medicine Year


OPHTH 8015 Neuro-Ophthalmology (Clinical Elective)

This elective will be offered by invitation only to select fourth-year medical students with a career interest in Neuro-Ophthalmology. During the four-week rotation, students will be busy in the Neuro-Ophthalmology clinic. Students will be expected to work-up new patients and present them to the Neuro-Ophthalmology attending. After clinic students should read about diagnoses encountered in clinic. In addition, there will be required reading. Comprehension of the reading will be assessed by scheduled quizzes which will then be reviewed with the student by one of three faculty members. There may be opportunities to join the operating room for strabismus surgery. Interested students will be encouraged to engage in a research project with one of the faculty members, although this is not required for the rotation. This will be a busy clinical elective; students can expect to spend ten half-days working in clinic or the OR per week. By the end of the rotation, students will feel comfortable recording a chief complaint, focused Neuro-Ophthalmic history, and performing a Neuro-Ophthalmic examination. Students should achieve resident level knowledge of common Neuro-Ophthalmic pathology.

Credit 2 units.

Typical periods offered: Medicine Year


OPHTH 8030 Orbital and Oculofacial Plastic Surgery (Clinical Elective)

Hands-on experience with clinical and surgical aspect of Orbital and Oculofacial Plastic Surgeons. Students will work with Dr. Couch and Dr. Maamari in the clinic and the operating room in the care of diverse patients both on the pediatric and adult sides.

Credit 2 units.

Typical periods offered: Medicine Year


OPHTH 9100 Ophthalmology Advanced Clinical Rotation (ACR)

On the Ophthalmology Advanced Clinical Rotation, medical students will rotate on the ophthalmology adult consult service, the University Eye Service clinic, and the subspecialty clinics of the full time faculty of the Department of Ophthalmology and Visual Sciences (cornea, glaucoma, oculoplastics, neuro-ophthalmology, pediatric ophthalmology). Students will care for patients of all ages and backgrounds, and ophthalmic diseases seen will range from common eye conditions to complex diseases requiring subspecialty care.
   
In clinic and on consults, students will perform the ophthalmic history and physical examination and also develop their ability to diagnose, manage, and treat common ophthalmic conditions. In the operating room, students will participate in all phases of perioperative patient care and learn basic ophthalmic surgical principles and techniques.
   
Academic curriculum for the rotation will include weekly case presentations with ophthalmology faculty, resident lectures and conferences, and weekly departmental grand rounds. Each student will also present a case at grand rounds during the final week of the rotation with the assistance of a resident mentor.
   
Students will participate in ophthalmology call approximately one evening per week. During that time, the medical student is expected to be present to work with the primary call ophthalmology resident.

Credit 4 units.

Typical periods offered: Medicine Year